Neonatal exchange transfusions in the 21st century: A single hospital study
| Autor: | Helen Savoia, Lex W. Doyle, Nina Ziegler, Lisa M Fox, Helen Elizabeth Chitty |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Pediatrics
medicine.medical_specialty business.industry medicine.medical_treatment Exchange transfusion Retrospective cohort study Jaundice Respiratory support Mean difference Pediatrics Perinatology and Child Health medicine ABO incompatibility Clinical staff medicine.symptom business Haemolytic disease |
| Zdroj: | Journal of Paediatrics and Child Health. 49:825-832 |
| ISSN: | 1034-4810 |
| DOI: | 10.1111/jpc.12290 |
| Popis: | Aim In the 21st century, neonatal exchange transfusions (ETs) are uncommon procedures usually performed in tertiary neonatal units. As junior clinical staff now lack familiarity with the procedure, it is important to maintain awareness of its complications in order to manage clinical risks and counsel parents appropriately. The study aims to analyse the ET rate, its indications and its associated complications, in a single tertiary centre in the 21st century. Methods This is a retrospective cohort study of all infants receiving ET from 1 January 2001 to 31 December 2010 at the Royal Women's Hospital, Melbourne. Results Sixty-four ETs were performed in 51 infants, an average of 6.4 ETs per year. Forty-nine (96%) infants were exchanged for hyperbilirubinaemia and two (4%) for anaemia. Thirty-six (71%) infants had Rhesus haemolytic disease of the newborn and six (12%) had ABO incompatibility. Six infants were intubated and mechanically ventilated after ET; these infants were significantly more acidotic during the ET than those who were never on respiratory support (mean pH 7.153 and 7.309 respectively, mean difference −0.156, 95% CI −0.196 to −0.116, t = 7.85, P |
| Databáze: | OpenAIRE |
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