ChemInform Abstract: Expedient Approach to Chiral Cyclobutanones: Asymmetric Synthesis of Cyclobut-G

Autor:	Susannah C. Coote, Jean-François Poisson, Andrew E. Greene, Benjamin Darses
Rok vydání:	2008
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Cyclobut-G Chemistry Stereochemistry Nucleic acid Enantioselective synthesis General Medicine Enol Alkyl
Zdroj:	ChemInform. 39
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200831074
Popis:	An efficient one-pot asymmetric synthesis of cyclobutanones from chiral enol ethers is described. The approach is illustrated with alkyl- and functionalized alkyl-substituted enol ethers (nine examples). A new enantioselective synthesis of cyclobut-G (Lobucavir) could thus be achieved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::393702d3aa7a623b01af4d90b87e2afb https://doi.org/10.1002/chin.200831074 Zobrazit plný text záznamu Plný text