Catalytic asymmetric synthesis of a new class of CyPHOX ligands

Autor:	Hai-Hua Lu, Zhi-Min Xu, Fen Tan, Wei Gao, Meng-Yue Cao, Juan Liu
Rok vydání:	2019
Předmět:	Cyclohexane 010405 organic chemistry Aryl Organic Chemistry Enantioselective synthesis 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences Catalysis chemistry.chemical_compound chemistry Drug Discovery
Zdroj:	Tetrahedron. 75:3282-3291
ISSN:	0040-4020
DOI:	10.1016/j.tet.2019.04.050
Popis:	Four newly designed CyPHOX ligands with chiral cyclohexane scaffold replacing the previous planar aryl group of PHOX ligands, were efficiently prepared. The synthesis features a kinetically controlled asymmetric phos-Michael reactions of trisubstituted cyclic carboxylates, which is quite simple, reliable and scalable.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::392a783fe27895854e63f35f7522a48c https://doi.org/10.1016/j.tet.2019.04.050 Zobrazit plný text záznamu Full Text from ScienceDirect