A convenient one-pot synthesis of boroxoles from diboronic acid

Autor:	Loïc Tomas, Rodolphe Vatinel, Craig S. Harris, Veronique Parnet, Gilles Ouvry, Catherine Raffin, Bénédicte Drean, Claire Bouix-Peter, Kana Kunihiro, Guillaume Lafitte, Branislav Musicki, Jean-François Fournier, Frédéric Gaigne, Romain Pierre, Céline Bonneaud
Rok vydání:	2017
Předmět:	Scope (project management) 010405 organic chemistry Chemistry Organic Chemistry Drug Discovery One-pot synthesis Substrate (chemistry) Organic chemistry 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Butyl lithium
Zdroj:	Tetrahedron Letters. 58:3757-3759
ISSN:	0040-4039
Popis:	The preparation of the boroxole motif traditionally relies on a 3-step process and the use of n -butyl lithium that can limit substrate scope. Herein during our exploration toward novel RORγ inhibitors, we identified a convenient one-pot preparation of the motif in good yields with good substrate scope.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::391ca91636278c61a11cf3907054cbb2 https://doi.org/10.1016/j.tetlet.2017.08.011 Zobrazit plný text záznamu Full Text from ScienceDirect