Current Applications of Susceptibility Weighted Images in Pediatric Neurological Diseases
| Autor: | Nivan Hany Khater, Sarah Mohamed Mahmoud Abdelwahab, Yasser Abdelazem |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | QJM: An International Journal of Medicine. 114 |
| ISSN: | 1460-2393 1460-2725 |
| DOI: | 10.1093/qjmed/hcab106.068 |
| Popis: | Background SWI provides information and helps in the differential diagnosis of different pediatric neurological diseases as it accentuates the paramagnetic properties of intravascular hemoglobin in the brain, and is sensitive for other extravascular blood products such as de-oxy-hemoglobin, hemosiderin, calcifications and air. Objectives The purpose of this article is to present and discuss the susceptibility weighted imaging signal characteristics of the normal pediatric brain and those of a variety of pediatric brain pathologic abnormalities. We aimed to evaluate the influence of the SWI signal pattern in current pediatric neurological diseases we will make a comprehensive review and discuss the utility of SWI in pediatric neuroimaging in establishing the diagnosis, differential diagnosis, and also understanding the pathomechanism of various paediatric brain pathologies Materials and Methods This study was held in MRI imaging unit of radiology department of Ain Shams university hospital and included 34 patients pediatric age group with different neurological diseases focusing on stroke, haemorrhage, tumour, calcifications and vascular malformation. Results We included 34 pediatric patients with different neurological diseases that commonly seen in our department and in which 26 (76.5 % )of them gained more detailed information from SWI sequence than conventional sequences, we found that SWI shows better sensitivity 100 % compared to conventional sequences that were 79.4 % in other means SWI was clinically and statistically significant . Conclusion Its high susceptibility for blood products, iron depositions, and calcifications makes susceptibility-weighted imaging an important additional sequence for the diagnostic workup of pediatric brain pathologic abnormalities that should be routinely added in our department. Compared with conventional MRI sequences, susceptibility-weighted imaging may show lesions with better detail and higher sensitivity. Familiarity with the pediatric susceptibility-weighted imaging signal variance is essential to prevent misdiagnosis. |
| Databáze: | OpenAIRE |
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