Synthesis of enantiopure aza-analogues of cocaine

Autor:	N.Miranda Teerhuis, W. Nico Speckamp, Henk Hiemstra
Rok vydání:	1997
Předmět:	Enantiopure drug Nucleophile Chemistry Organic Chemistry Drug Discovery Organic chemistry Biochemistry
Zdroj:	Tetrahedron Letters. 38:159-162
ISSN:	0040-4039
Popis:	An enantiopure aza-analogue of pseudo-cocaine was synthesized starting from a 5-substituted 3-pyrazolidinone by using an N-acylhydrazonium ion cyclization with a dioxenone nucleophile as the key step.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::38fa1f2192e1bafe798115f1dacf664f https://doi.org/10.1016/s0040-4039(96)02242-3 Zobrazit plný text záznamu Full Text from ScienceDirect