Bronchoalveolar lavage in asthmatic children: Evidence of neutrophil activation in mild-to-moderate persistent asthma
| Autor: | Marta Gheno, C. Panizzolo, Diego Faggian, Franca Giusti, Angelo Barbato, Laura Sainati, Elisabetta Favero, Mario La Rosa, Lidia Pesscolderungg |
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| Rok vydání: | 2001 |
| Předmět: |
Allergy
Eosinophil cationic protein medicine.diagnostic_test biology business.industry Immunology Respiratory disease Granulocyte medicine.disease respiratory tract diseases medicine.anatomical_structure Bronchoalveolar lavage Myeloperoxidase Pediatrics Perinatology and Child Health medicine biology.protein Absolute neutrophil count Immunology and Allergy business Asthma |
| Zdroj: | Pediatric Allergy and Immunology. 12:73-77 |
| ISSN: | 0905-6157 |
| DOI: | 10.1034/j.1399-3038.2001.012002073.x |
| Popis: | Little information is available on cell profiles and mediator production in the lower airways of children with asthma by comparison with the adult population. To study the bronchoalveolar lavage (BAL) cell profiles and production of eosinophil cationic protein (ECP) and myeloperoxidase (MPO) in childhood bronchial asthma, a retrospective study was performed in 29 children (13 allergic asthmatic children and 16 controls). Six of the asthmatics had mild-to-moderate persistent disease and seven had intermittent asthma. The BAL cell count and ECP and MPO values of asthmatic children were compared with those from 16 controls. The asthmatic patients had higher values than controls for the total cell count (p=0.08), for neutrophils (p=0.02), and for ECP and MPO (p |
| Databáze: | OpenAIRE |
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