Atypical familial Mediterranean fever developed in a long-term hemodialysis patient
| Autor: | Noriaki Matsui, Takayuki Toda, Yohei Kono, Ayumu Nomizu, Yutaro Mori, Mariko Ichijo, Yoshitatsu Ohara, Toshiyuki Makino, Dai Kishida, Namiko Kobayashi |
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| Rok vydání: | 2018 |
| Předmět: |
Pediatrics
medicine.medical_specialty medicine.diagnostic_test business.industry medicine.medical_treatment Amyloidosis 030232 urology & nephrology Familial Mediterranean fever Hematology Long term hemodialysis medicine.disease 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Nephrology medicine Colchicine Hemodialysis Fever of unknown origin business Serositis 030217 neurology & neurosurgery Genetic testing |
| Zdroj: | Hemodialysis International. 22:E19-E22 |
| ISSN: | 1492-7535 |
| DOI: | 10.1111/hdi.12628 |
| Popis: | Familial Mediterranean Fever (FMF) is usually an autosomal recessive autoinflammatory disease characterized by recurrent attacks of fever and serositis. FMF develops before the age of 20 years in 90% of patients. It has intervals of 1 week to several years between attacks, which leads to renal dysfunction-amyloidosis. We report a case of atypical FMF that developed in a long-term hemodialysis patient. A 65-year-old Japanese female undergoing hemodialysis for 32 years was referred to our hospital with a fever of unknown origin (FUO) following cervical laminoplasty. The fever occurred as recurrent attacks accompanied by oligoarthralgia of the left hip and knee. We suspected FMF because of recurrent self-limited febrile attacks, although the patient showed atypical clinical features such as late-onset and highly frequent attacks. After receiving treatment, she achieved a complete response to colchicine. Therefore, a diagnosis of FMF was made based on the Tel-Hashomer criteria, which was confirmed by genetic testing. The case suggests that FMF may be of note in long-term hemodialysis patients developing FUO. |
| Databáze: | OpenAIRE |
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