Comparison of the healing status in suture-less end-to-end intestinal anastomosis using TachoSil with classic two-layer anastomosis in rats
| Autor: | Iman Shamohammadi, Hadi Hadavi, Bahram Pourseidi, Alireza Amirbeigi, Shahriar Dabiri, Khatereh Dehghani, Akram Arabi, Mohammadreza Ghasemian Moghaddam, Amir Hossein Pourdavood, Maryam Dehghankhalili |
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| Rok vydání: | 2019 |
| Předmět: |
Gangrene
medicine.medical_specialty 040301 veterinary sciences business.industry Ileum 04 agricultural and veterinary sciences TachoSil Anastomosis medicine.disease Thrombosis Pathology and Forensic Medicine Surgery 0403 veterinary science Ileocecal valve medicine.anatomical_structure Suture (anatomy) Medicine Anatomy Vicryl business |
| Zdroj: | Comparative Clinical Pathology. 29:463-467 |
| ISSN: | 1618-565X 1618-5641 |
| DOI: | 10.1007/s00580-019-03071-1 |
| Popis: | The classical two-layer anastomosis has been experimentally compared with anastomosis using synthetic TachoSil in terms of pre- and post-surgical symptoms and healing status of the anastomotic area in rats. Thirty-six adult male rats were randomly allocated into two groups: in group C (control), classic anastomosis was performed in the ileum of the small intestine, 10 cm away from the ileocecal valve using Vicryl 5-0 interrupted suture; group S (study) received anastomosis in the same area but with TachoSil using three sutures (mesenteric, anti-mesenteric, and anterior wall as suture-less method). The obtained results were analyzed by SPSS20 software, using Chi-square test. Based on the obtained results, group C had more favorable anastomotic healing than group S. Actually, the fibroblast and collagen were seen in most cases of the control rats, while healing was stopped in group S (TachoSil group) in early stages due to thrombosis and vasculitis gangrene. According to the findings, TachoSil patch cannot be advised for safe use in suturing the less small-bowel anastomosis. |
| Databáze: | OpenAIRE |
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