Role of Leucocytes and Serum in Streptococcidal Activity of Blood

Autor:	F. D. Gunn, Floyd Boys
Rok vydání:	1934
Předmět:	Lysis biology Phagocytosis biology.organism_classification Bactericidal effect General Biochemistry Genetics and Molecular Biology Bacteria Intracellular Microbiology
Zdroj:	Experimental Biology and Medicine. 32:27-31
ISSN:	1535-3699 1535-3702
Popis:	ConclusionsThe power of defibrinated blood to inhibit the growth of or destroy streptococci is dependent upon the presence of surviving leucocytes and is roughly proportional to the number of leucocytes, other factors being equal. A minimal number of leucocytes is necessary for the demonstration of the bactericidal effect. The bacteria are removed by phagocytosis and finally destroyed by intracellular lysis. Complement is not necessary for tlie bactericidal action of defilxinated hlootl or serum. The lractericidal element in defibrinated blood which is effective against streptococci is not destroyed by heating the separated serum at 55-C. for 30 minutes. The results of a small number of tests suggest that the heating of the serum even at 68°C. does not impair the bactericidal effect of the restored defibrinatetl blood.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::38d247f18c28c8843fc1d3b3c44c0ea8 https://doi.org/10.3181/00379727-32-7542c Zobrazit plný text záznamu