| Autor: | L. M. Belkina, M. G. Pshennikova, Yu. V. Arkhipenko, T. N. Kirillina |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Myocardial ischemia biology August Rats business.industry Ischemia General Medicine medicine.disease General Biochemistry Genetics and Molecular Biology Nitric oxide Nitric oxide synthase chemistry.chemical_compound Endocrinology chemistry Internal medicine Ventricular fibrillation medicine Cardiology biology.protein cardiovascular diseases Myocardial infarction business |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 133:540-543 |
| ISSN: | 0007-4888 |
| Popis: | As differentiated from Wistar rats, myocardial ischemia and reperfusion produce no ventricular fibrillation in August rats. Pretreatment with nitric oxide synthase inhibitor Nw-nitro-L-arginine increased mortality rate in August rats with acute myocardial infarction from 20 to 40%. Under these conditions mortality rate in Wistar rats increased from 50 to 71%. Interstrain differences in the resistance of these animals to the arrhythmogenic effect of ischemia are probably associated with higher activity of the nitric oxide system in August rats compared to Wistar rats. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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