‘Click’ synthesis of cobalt bis(dicarbollide)–cholesterol conjugates

Autor:	Irina D. Kosenko, Zheyu Shen, Akim V. Shmal’ko, Anna A. Druzina, Andrey Semioshkin, Ekaterina P. Andreichuk, Igor B. Sivaev, Vladimir I. Bregadze, Swadhin K. Mandal, Olga B. Zhidkova
Rok vydání:	2019
Předmět:	inorganic chemicals Liposome 010405 organic chemistry Cholesterol chemistry.chemical_element General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Cycloaddition 0104 chemical sciences Neutron capture therapy of cancer chemistry.chemical_compound chemistry Drug delivery lipids (amino acids peptides and proteins) Boron Cobalt Conjugate
Zdroj:	Mendeleev Communications. 29:628-630
ISSN:	0959-9436
Popis:	New conjugates of cholesterol and cobalt bis(dicarbollide) were synthesized using ‘click’ cycloaddition of 3b-(2-azidoethyl) cholest-5-ene and acetylene-equipped cobalt bis(dicarbollides). The synthesized boronated cholesterols can be of interest for liposomal drug delivery for boron neutron capture therapy of cancer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::38bdf1b74cfdfc1e06fae70740960f4c https://doi.org/10.1016/j.mencom.2019.11.007 Zobrazit plný text záznamu Full Text from ScienceDirect