Characteristics, management, and in-hospital mortality of acute myocardial infarction in teh 'real world' in France
| Autor: | Muriel Rabilloud, Hugues Milon, Cheneau E, Excoffier S, René Ecochard, Colin C, de Gevigney G, François Delahaye, Cao D |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
medicine.medical_specialty
Multivariate analysis business.industry Mortality rate medicine.medical_treatment General Medicine Odds ratio Thrombolysis medicine.disease QT interval Surgery Internal medicine Cohort Medicine Myocardial infarction Cardiology and Cardiovascular Medicine business Killip class |
| Zdroj: | Acta Cardiologica. 55:357-366 |
| ISSN: | 0001-5385 |
| DOI: | 10.2143/ac.55.6.2005767 |
| Popis: | Objective - The prospective PRIMA study (Prise en charge de l'Infarctus du Myocarde Aigu; management of acute Ml) sought to determine characteristics, management, and in-hospital mortality of myocardial infarction (MI), regardless of age and hospital facilities, in the real world in a region in France. Methods and results - Data were prospectively collected in all patients with Ml admitted in all hospitals in three departments in the Rhone-Alpes region between September I, 1993 and January 31, 1995. 2,519 patients (68% men; mean ± SD: 68 ± 14 years) were included. Time from onset of symptoms to admission was I in 33%. The overall rate of thrombolysis was 36%. It was significantly higher in men than in women, in younger patients than in older patients, in lower Killip classes, in Q wave MI, and when the delay before initial medical intervention was < 6 hours. After age-adjustment, there was no difference between men and women for thrombolysis rate (odds ratio women/men: 0.92; p = 0.10). During the first 5 days, Killip class worsened in 17%. In-hospital mortality rate was 14%. Multivariate analysis identified age, anterior location, presence of Q waves, and higher Killip classes as significant predictors of in-hospital mortality. Conclusions - This large unselected cohort revealed that among patients with Ml in a French region, there was a high proportion of elderly patients, a low rate of thrombolysis, and a high in-hospital mortality. |
| Databáze: | OpenAIRE |
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