Mutations Induced in the lacI Gene of E. coli by 1-Nitroso-8-Nitropyrene and Furylfuramide: The Influence of Plasmid pKM101 and Excision Repair on the Mutational Spectrum

Autor:	A. J. E. Gordon, Barry W. Glickman, D.R. McCalla, Iain B. Lambert, T. A. Chin, D. W. Bryant
Rok vydání:	1990
Předmět:	food.ingredient biology Food additive Nitroso Lac repressor biology.organism_classification Frameshift mutation chemistry.chemical_compound food chemistry Biochemistry Furylfuramide Gene Bacteria Nucleotide excision repair
Zdroj:	Nitroarenes ISBN: 9781461366942
DOI:	10.1007/978-1-4615-3800-4_15
Popis:	Nitrated polyaromatic hydrocarbons (NO2PAH) and nitroheterocyclic compounds are of potential human health importance. NO2PAH are emitted into the environment as byproducts of combustion processes (1), while nitroheterocyclic compounds such as 5-nitrofuran derivatives have been widely used in both human and veterinary medicine, and as food additives and preservatives. Representatives of each of these chemical classes are potent mutagens in bacteria, and induce tumors in rodents (1,2).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::38b77f48b9c2996f7afc0bc9b02a688e https://doi.org/10.1007/978-1-4615-3800-4_15 Zobrazit plný text záznamu