Hyperplasie thymique et maladie de Basedow : une association non fortuite. Cas clinique et revue de la littérature
| Autor: | A. Greder, J.P. Beressi, C. Collet-Gaudillat, R. Cerceau, Y. Cordoliani, B. Fraleu-Louer, R. Meckenstock, G. Petit-Aubert, V. Desforges-Bullet |
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| Rok vydání: | 2011 |
| Předmět: |
Autoimmune disease
endocrine system Pathology medicine.medical_specialty endocrine system diseases Medical treatment business.industry Endocrinology Diabetes and Metabolism Graves' disease Thyroid Disease Association General Medicine Hyperplasia medicine.disease Dermatology Endocrinology medicine.anatomical_structure Immunopathology medicine Thymus hyperplasia business |
| Zdroj: | Annales d'Endocrinologie. 72:304-309 |
| ISSN: | 0003-4266 |
| Popis: | Thymus hyperplasia and Graves' disease association is not well known and is probably not incidental. We report the case of a young woman affected with Graves' disease in which a retrosternal mass was disclosed during a neck ultrasonographic-examination and confirmed by chest CT-examination. Follow-up ultrasound survey showed a decrease in the thymic mass size. Because of various antithyroid drugs allergy, a surgical procedure was performed, during which both her thyroid and thymic mass were removed. The histopathologic examination of this mass confirmed the hyperplasic nature of the thymic bulging. Ninety-one cases of thymus hyperplasia and Graves' disease association have been reported in literature, of which 20 were histologically confirmed. Among these cases 35 showed a thymic mass regression under medical treatment alone. Accordingly, surgical procedures are most frequently unnecessary in such associations because of the thymic mass decrease incurred by antithyroid drug treatment. |
| Databáze: | OpenAIRE |
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