A Beckmann rearrangement initiated by trifluoromethanesulfonic anhydride in the synthesis of compounds containing a new pyrazolo[3',4':5,6]pyrido[3,2-b]azepine heterocyclic system

Autor:	M. V. Vovk, Marta S. Yagodkina-Yakovenko, Sergey Yu. Suykov, Georgiy G. Yakovenko
Rok vydání:	2021
Předmět:	chemistry.chemical_compound 010405 organic chemistry Chemistry Trifluoromethanesulfonic anhydride Organic Chemistry Beckmann rearrangement Azepine 010402 general chemistry 01 natural sciences Medicinal chemistry Pyrrolidine 0104 chemical sciences
Zdroj:	Chemistry of Heterocyclic Compounds. 57:199-206
ISSN:	1573-8353 0009-3122
DOI:	10.1007/s10593-021-02893-8
Popis:	N-Boc-5-formylpyrazol-4-amines reacted with 1,3-cyclohexanediones in AcOH–1,4-dioxane medium in the presence of pyrrolidine, resulting in the formation of pyrazolo[4,3-b]quinolin-8-one derivatives that were converted into the respective oximes. A reaction of the latter with trifluoromethanesulfonic anhydride under mild conditions was used to synthesize hexahydropyrazolo[3',4':5,6]pyrido[3,2-b]-azepin-4-ium trifluoromethanesulfonates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::386cd4d2bdd107facfcda02f5b197bbc https://doi.org/10.1007/s10593-021-02893-8 Zobrazit plný text záznamu Plný text ve formátu PDF