Autor:	Frédéric Taran, Evelia Rasalofonjatovo, Simon Specklin, Olivier Loreau, Sandra Gabillet
Rok vydání:	2015
Předmět:	Amidine chemistry.chemical_compound Tandem Chemistry Intramolecular cyclization Fluorescent protein General Medicine Chromophore Combinatorial chemistry Phosphine Catalysis Umpolung
Zdroj:	ChemInform. 46
ISSN:	0931-7597
DOI:	10.1002/chin.201514163
Popis:	A simple and efficient method for constructing 4-arylidene-5-imidazolones was developed using a phosphine-catalyzed tandem umpolung addition and intramolecular cyclization of amidine pronucleophiles on arylpropiolates. The reaction offers a robust route to heterocycle analogues of the fluorescent protein chromophores.
Databáze:	OpenAIRE
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