Evaluation of the role of unconjugated hyaluronic acid repetitive injection during the primary repair of flexor tendons in no man’s land: a randomized control trial
| Autor: | Youssif Ahmed Khachaba, Tarek Ashour, Khaled Makeen ElRefaei, Ahmed Safwat Salem, Omar Mohamed Nouh |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Flexor tendon business.industry 030230 surgery Group B law.invention Surgery 03 medical and health sciences Tendon sheath chemistry.chemical_compound Plastic surgery 0302 clinical medicine Randomized controlled trial chemistry law 030220 oncology & carcinogenesis Hyaluronic acid medicine No man s land Range of motion business |
| Zdroj: | European Journal of Plastic Surgery. 42:463-472 |
| ISSN: | 1435-0130 0930-343X |
| Popis: | Zone 2 flexor tendon injuries are prone to poor results following repair due to adhesions. Different repair methods and physiotherapy protocols have been devised to improve outcomes, with variable results. Hyaluronic acid (HA) is a polysaccharide produced by the innermost layer of the tendon sheath that facilitates gliding in zones where the sheath is continuous. Sixty-two flexor tendons that were repaired using a double-stranded core suture were divided between groups A (n = 32) and B (n = 30). In the former, non-cross-linked HA was repeatedly instilled at the repair site, with a total of three injections per digit. The repair outcomes were assessed using the Strickland criteria, the ratio of total active motion to total passive motion (TAM/TPM), and active range of motion (AROM) for individual joints. A total of 31.1% of group A patients had excellent to good outcomes in contrast to 13.3% in group B. The mean difference in TAM was 105° in group A and 71° in group B (p value ˂ 0.05). The mean TAM/TPM was 0.65 in group A and 0.56 in group B (p value = 0.06). HA significantly improves the results of flexor tendon repair in zone 2. Level of Evidence: I. |
| Databáze: | OpenAIRE |
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