| Popis: |
1. 1. After the intravenous injection of glucose into normal male rats, we have measured the plasma-insulin activity, the glucose uptake of the diaphragm and of epididymal adipose tissue from 5–90 min after the injection. We have observed an increased uptake of glucose by the diaphragm and a rise of insulin in the blood 10 min after the injection. In the adipose tissue we have observed an inhibition of glucose uptake at all times up to 60 min. 2. 2. 10 min after the injection of l -leucine the blood insulin rises and there is an increase in the uptake of glucose by the diaphragm and by the epididymal adipose tissue. 3. 3. The inhibition of uptake of glucose by adipose tissue, observed after intravenous injection of glucose, is not produced in adrenalectomized rats. It is suggested that hyperglycemia produces secretion of glucocorticoids which are responsible for the inhibiton of the uptake of glucose in adipose tissue. |
