Small Bowel Electrical Activity in an Experimental Model of Hypochlorhydria

Autor:	I. G. Vilkova, N. S. Tropskaya, T. V. Chernen'kaya, T. S. Popova
Rok vydání:	2022
Předmět:	General Medicine
Zdroj:	Journal Biomed. 18:58-61
ISSN:	2713-0428 2074-5982
Popis:	Variations in the basic parameters of the electrical activity of the small intestine in rats were studied using an experimental model of hypochlorhydria caused by an intragastric administration of rabeprazole for 16 days. Hypochlorhydria was found to lead to an increased duration of irregular electric activity and a reduction in the period of quiescence, which indicates an increase in uncoordinated contractions of the small intestine. A decrease in the number of migrating myoelectric complexes and, consequently, a partial suppression of propulsive peristalsis contributes to an excessive bacterial overgrowth in the proximal small intestine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::384160dca459a618cd3a7f1744d082b9 https://doi.org/10.33647/2074-5982-18-3-58-61 Zobrazit plný text záznamu