Analysis of Fine Needle Aspiration Cytology of the Breast
| Autor: | Jae Hyuk Lee, Sang-Woo Juhng, Jong Hee Nam, Chan Choi, Young Hyo Choi, Yoo Duk Choi |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
Histology medicine.diagnostic_test business.industry Physical examination General Medicine medicine.disease Malignancy Pathology and Forensic Medicine Surgery Fine-needle aspiration Breast cancer Cytology Predictive value of tests Biopsy Medicine Mammography Radiology business |
| Zdroj: | Acta Cytologica. 48:801-806 |
| ISSN: | 1938-2650 0001-5547 |
| Popis: | Objective To evaluate the accuracy of fine needle aspiration (FNA) cytology of the breast and to ascertain its usefulness. Study design The authors reviewed 1,297 cases of FNA cytology of the breast which were performed at Chonnam National University Hospital from 1999 to 2002. Cytologic diagnoses were compared with histologic diagnoses in 457 cases that underwent both cytologic and histologic examination. Results Of 1,297 cases, 1,201 (92.6%) were satisfactory and 96 (7.4%) unsatisfactory. Subsequent histologic examination was performed on 291 cases (29.7%) out of 981 "benign" lesions, 28 (73.7%) of 38 "suspicious," 124 (68.1%) of 182 "malignant" and 14 (14.6%) of 96 "unsatisfactory." FNA cytology revealed 77.7% sensitivity, 99.2% specificity, 98.4% positive predictive value and 88.0% negative predictive value. Diagnostic accuracy was 91.1%. Of the 291 benign cases on cytology, 35 cases were malignancy on histology. Of the 124 cases reported as malignant, 2 were benign. Interpretive error was the leading cause of false positive diagnoses. Conclusion Although FNA cytology is a useful diagnostic procedure for the evaluation of breast lesions, it should be combined with other diagnostic modalities, such as physical examination, ultrasonography and mammography. |
| Databáze: | OpenAIRE |
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