Yb(OTf)3-catalyzed Mannich-type reaction of a chiral non-racemic silyloxypyrrole

Autor:	Angèle Chiaroni, Bruno Dudot, Jacques Royer
Rok vydání:	2000
Předmět:	chemistry.chemical_classification chemistry Organic Chemistry Drug Discovery Diastereomer Organic chemistry Amine gas treating Selectivity Biochemistry Aldehyde Chemical correlation Catalysis
Zdroj:	Tetrahedron Letters. 41:6355-6359
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)01055-8
Popis:	A Yb(OTf)3-catalyzed Mannich-type reaction of the chiral non-racemic silyloxypyrrole 2 is described. The three-component (silyloxypyrrole, aldehyde and amine) reaction allowed the use of aromatic as well as aliphatic enolisable aldehydes. The erythro selectivity was proved by chemical correlation and X-ray analysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::37faa7bb4b263f77c998322a1f7abf22 https://doi.org/10.1016/s0040-4039(00)01055-8 Zobrazit plný text záznamu Full Text from ScienceDirect