| Autor: |
Jie Lei, yuanyuan Fan, Cunxin Bian, Songtao Yuan, Yurong Ye, Kun Huang, Qiang Chen, Zizhong Hu, Qinghuai Liu, Bin Yang, Ping Xie |
| Rok vydání: |
2022 |
| DOI: |
10.21203/rs.3.rs-1982162/v1 |
| Popis: |
Objectives. To characterize the microstructural alterations of peripapillary choriocapillaris in young adult high myopes using optical coherence tomography angiography (OCTA) and to explore factors involved in the alterations. Methods. This cross-sectional control study included 205 eyes (95 with high myopia and 110 with mild-moderate myopia). The choroidal vascular network was imaged using OCTA, and the images underwent manual adjustments to determine the peripapillary atrophy (PPA)-β zone and microvascular dropout (MvD). The area of MvD and PPA-β zone, spherical equivalent (SE), and axial length (AL) were collected and compared across groups. Results. The MvD was identified in 195 eyes (95.1%). Highly myopic eyes exhibited significantly greater area of PPA-β zone (1.221 ± 0.073 vs. 0.562 ± 0.383 mm2, P = 0.001) and MvD (0.248 ± 0.191 vs. 0.089 ± 0.082 mm2, P P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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