Carrier state of GBS in the aspect of perinatal antibiotic therapy in 2007–2011
| Autor: | Witold Malinowski, Olimpia Sipak-Szmigiel, Sławomir Szymański, Katarzyna Szczerba, Violetta Konstanty-Kurkiewicz |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pregnancy
medicine.medical_specialty business.industry Obstetrics Incidence (epidemiology) Amniotic sac General Medicine medicine.disease_cause medicine.disease medicine.anatomical_structure Streptococcus agalactiae Statistical significance medicine Childbirth Apgar score Antibiotic prophylaxis business |
| Zdroj: | Pomeranian Journal of Life Sciences. 64 |
| ISSN: | 2450-4637 |
| DOI: | 10.21164/pomjlifesci.399 |
| Popis: | Introduction: A significant decline in the proportion of the perinatal mortality of foetuses and newborns has been observed in recent years. The use of perinatal antibiotic therapy in order to reduce the risk of infection, including strains of group B Streptococcus (GBS) – Streptococcus agalactiae contracted during birth, is one of the reasons for this outcome. Materials and methods: Material for the study was obtained from medical record data covering 1,328 live births of individual infants and their mothers. The analysed continuous parameters are described with appropriate numbers, arithmetic mean, standard deviation, and median, minimum and maximum values. Discrete parameters (qualitative) are expressed as percentages (fractions). The arithmetic means between groups were compared using Student’s t-test. For analysis of fractions the χ2 test was used with the Yates correction (for a small number of cells). The level of statistical significance was accepted at p < 0.05. Results: The mean age of women giving birth was estimated at 27.5 ±5.1 years. The mean duration of pregnancy was 39.2 ±1.6 weeks. The mean time from the rupture of the amniotic sac to completion of birth was 352.2 ±925.2 minutes. The total time of the childbirth of an infected newborn was significantly longer then the birth of a healthy newborn (453.3 vs 383.8; p < 0.0001). The Apgar score was significantly higher in healthy newborns then in infected ones (9.3 vs 8.6; p < 0.0001). The percentage of treated pregnant women scored 26.81%, while those with a positive culture was 78.43% (p < 0.0001). Conclusions: The use of perinatal antibiotic prophylaxis reduces the incidence of early GBS infections in newborns. The use of perinatal antibiotic therapy in the absence of GBS culture is not a common procedure. However, by comparing years 2007–2011, it is practiced more and more. The occurrence of the GBS carrier state is common. |
| Databáze: | OpenAIRE |
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