The Effect of Atrial Pressure Changes and Cardiac Nerves on Plasma Atrial Natriuretic Peptide Levels

Autor: Nihat Okçu, F. Ayse Pac, Ebubekir Bakan, Hikmet Koçak, Arif Yilmaz, Ahmet Basoglu, M. Derya Onuk, Azman Ateş, Mehmet Gundogdu
Rok vydání: 1993
Předmět:
Zdroj: Vascular Surgery. 27:128-132
ISSN: 0042-2835
DOI: 10.1177/153857449302700209
Popis: The authors researched the association between plasma atrial natriuretic peptide (ANP) levels and atrial pressure changes and cardiac nerves in 14 dogs. The dogs were divided into two groups, each group containing 7 dogs. In the second group, cardiac denervation was performed. Left atrial pressure was in creased by creating partial mitral obstruction in both groups. In the second stage, after atrial pressures were decreased to previous values, the dogs were bled. Eventually, atrial pressures were decreased below the normal value. Plasma ANP levels and right and left atrial pressures were determined in all stages. It was concluded that ANP was released from the atria by a direct effect of stretching of the atrial wall and that there was no specific effect of cardiac nerves on ANP release.
Databáze: OpenAIRE