Age-based assessment of cell-free DNA genomic profiles in metastatic castration-resistant prostate cancer (mCRPC)

Autor:	Andrea Knox, Heidi Fettke, Christine Hauser, Patricia Bukczynska, Nicole Ng, Siavash Foroughi, Lisa-Jane K. Graham, Kate Lynette Mahon, Winston Tan, Tiantian Zheng, Chao Dai, Pan Du, Shidong Jia, Lisa Horvath, Manish Kohli, Arun Azad, Edmond Michael Kwan, Amy Wang
Rok vydání:	2022
Předmět:	Cancer Research Oncology
Zdroj:	Journal of Clinical Oncology. 40:150-150
ISSN:	1527-7755 0732-183X
Popis:	150 Background: With the evolving use of targeted therapies exploiting genomic vulnerabilities in mCRPC, screening patients for sensitizing alterations is of increasing relevance. However, the influence of age on the detection of relevant genomic alterations is incompletely understood. In this study, we compared the cell-free DNA (cfDNA) profiles of younger (age
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::37e65636154f765d52f79d055a77b2bc https://doi.org/10.1200/jco.2022.40.6_suppl.150 Zobrazit plný text záznamu