A case of myoepithelioma in the palate

Autor: Munehisa Okada, Kaoru Kusama, Hisao Shigematsu, Seiji Suzuki, Hiroko Shida, Hideaki Sakashita
Rok vydání: 2004
Předmět:
Zdroj: Japanese Journal of Oral & Maxillofacial Surgery. 50:87-90
ISSN: 2186-1579
0021-5163
DOI: 10.5794/jjoms.50.87
Popis: A 50-year-old man was referred to our hospital because of a growth in the right side of the hard plate. Radiographic and computed tomographic examinations showed a unilocular radiolucent lesion with a well-circumscribed margin, involving a palatal root of the first molar. Magnetic resonance imaging (T2-weighted) showed increased signal intensity of the tumor. A possible diagnosis of pleomorphic adenoma was made on biopsy, and partial maxillectomy was performed. There has been no evidence of recurrence as of 1 year 8 months after the operation.Histopathologically, the tumor was well encapsulated by fibrous tissue and consisted of elliptical or rounded cells, with homogenous eosinophlic cytoplasm and eccentrically placed nuclei. The pathological diagnosis was myoepithelioma. Immunohistochemically, S-100 protein, vimentin, glial fibrillary acidic protein (GFAP), actin, and wide keratin were positive. Immunoreactivity for 35β H11 or 34β E12 was not detected clearly or markedly. Cells positive for PCNA, MIB-1, or both were rare.
Databáze: OpenAIRE