Rare Sesquiterpenoids from the Shed Trunk Barks of the Critically Endangered PlantAbies beshanzuensisand Their Bioactivities

Autor:	Jia Li, Guo-Xun Yang, Ji-Yang Li, Jin-Feng Hu, Ke-Jun Cheng, Wen-Xuan Wang, Li-Xin Gao, Chang-Ling Hu, Juan Xiong
Rok vydání:	2016
Předmět:	Circular dichroism biology 010405 organic chemistry Chemistry Stereochemistry Abies beshanzuensis Organic Chemistry biology.organism_classification Ring (chemistry) 01 natural sciences Trunk Terpenoid 0104 chemical sciences 010404 medicinal & biomolecular chemistry Critically endangered Plant species Epimer Physical and Theoretical Chemistry
Zdroj:	European Journal of Organic Chemistry. 2016:1832-1835
ISSN:	1434-193X
DOI:	10.1002/ejoc.201600165
Popis:	Two rare rearranged cuparane-type sesquiterpenoid C-10 epimers [beshanzuenones A (1) and B (2)] and two bisabolane-type sesquiterpenoid spirolactones [beshanzuenones C (3) and D (4)] featuring an unusual [6/6/5]-fused tricyclic ring system were isolated from the shed trunk barks of Abies beshanzuensis, one of the critically endangered plant species in the world. The structures of these four new enone-containing sesquiterpenoids were determined by spectroscopic analyses and single-crystal X-ray diffraction or electronic circular dichroism (ECD) calculations. Compounds 1 and 2 showed considerable activity against the H3N2 virus, whereas 3 and 4 exhibited significant inhibition on PTP1B.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::37d3ce65bf1d47a6de4fba9006a360f8 https://doi.org/10.1002/ejoc.201600165 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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