Progress toward a novel C-terminal helix capping principle: Synthesis and properties of (S)-α-(2-aminoethyl)-methionine

Autor:	Eloise C. Young, D. S. Kemp
Rok vydání:	1994
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Methionine chemistry Terminal (electronics) Stereochemistry Group (periodic table) Helix capping Organic Chemistry Drug Discovery Peptide Biochemistry Combinatorial chemistry
Zdroj:	Tetrahedron Letters. 35:8315-8318
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)74395-4
Popis:	(S)-α-(2-aminoethyl)-methionine 9 ((s)-2,4-diamino-2-(3-thiabutyl)-butanoic acid) is synthesized in three steps from 1-benzoyl-2-tert--butyl-5-(3-thiabutryl)-oxazolidin-4-one. Neighboring group reactions of peptide derivatives of 9 are described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::37d2a0b9c6c875cd69412dcc5ef58e60 https://doi.org/10.1016/s0040-4039(00)74395-4 Zobrazit plný text záznamu