Synthesis, characterisation and evaluation of hyperbranched N-(2-hydroxypropyl) methacrylamides for transport and delivery in pancreatic cell lines in vitro and in vivo
| Autor: | Akosua B. Anane-Adjei, Nicholas L. Fletcher, Robert J. Cavanagh, Zachary H. Houston, Theodore Crawford, Amanda K. Pearce, Vincenzo Taresco, Alison A. Ritchie, Phillip Clarke, Anna M. Grabowska, Paul R. Gellert, Marianne B. Ashford, Barrie Kellam, Kristofer J. Thurecht, Cameron Alexander |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Biomaterials Science. 10:2328-2344 |
| ISSN: | 2047-4849 2047-4830 |
| Popis: | Hyperbranched polyHPMA materials penetrate deep into pancreatic cancer spheroids and a hyperbranched polymer-gemcitabine conjugate showed potency in vitro and in vivo. |
| Databáze: | OpenAIRE |
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