INTERFERON-γ AND BACTERIAL LIPOPOLYSACCHARIDE ACT SYNERGISTICALLY ON HUMAN NEUTROPHILS ENHANCING INTERLEUKIN-8, INTERLEUKIN-1β, TUMOR NECROSIS FACTOR-α, AND INTERLEUKIN-12 P70 SECRETION AND PHAGOCYTOSIS VIA UPREGULATION OF TOLL-LIKE RECEPTOR 4

Autor: Michal Pearl-Yafe, Itamar Shalit, Edith Flatau, Sara Werber, Ina Fabian, Drora Halperin
Rok vydání: 2007
Předmět:
Zdroj: Shock. 27:226-231
ISSN: 1073-2322
DOI: 10.1097/01.shk.0000239765.80033.37
Popis: In human neutrophils, interferon (IFN)-γ enhanced the expression of toll-like receptor 4 (TLR4), a crucial component of the signaling receptor complex for bacterial lipopolysaccharide (LPS). Lipopolysaccharide alone did not affect TLR4 expression, but costimulation with IFN-γ and LPS induced
Databáze: OpenAIRE