INTERFERON-γ AND BACTERIAL LIPOPOLYSACCHARIDE ACT SYNERGISTICALLY ON HUMAN NEUTROPHILS ENHANCING INTERLEUKIN-8, INTERLEUKIN-1β, TUMOR NECROSIS FACTOR-α, AND INTERLEUKIN-12 P70 SECRETION AND PHAGOCYTOSIS VIA UPREGULATION OF TOLL-LIKE RECEPTOR 4
Autor: | Michal Pearl-Yafe, Itamar Shalit, Edith Flatau, Sara Werber, Ina Fabian, Drora Halperin |
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Rok vydání: | 2007 |
Předmět: | |
Zdroj: | Shock. 27:226-231 |
ISSN: | 1073-2322 |
DOI: | 10.1097/01.shk.0000239765.80033.37 |
Popis: | In human neutrophils, interferon (IFN)-γ enhanced the expression of toll-like receptor 4 (TLR4), a crucial component of the signaling receptor complex for bacterial lipopolysaccharide (LPS). Lipopolysaccharide alone did not affect TLR4 expression, but costimulation with IFN-γ and LPS induced |
Databáze: | OpenAIRE |
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