A CORRELATIVE STUDY ON DETERMINANTS OF TIME DOMAIN MEASURES OF CARDIAC VAGAL FUNCTION IN HEALTHY SUBJECTS
| Autor: | Jeganathan P.S, Sathyanarayana K.N. Rao, Subbalakshmi Nk |
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| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Journal of Health and Allied Sciences NU. :004-008 |
| ISSN: | 2582-4953 2582-4287 |
| DOI: | 10.1055/s-0040-1703722 |
| Popis: | Introduction: E: I ratio and r-MSSD are known indicators of cardiac vagal activity. But their determinants are unclear. Objective: To evaluate the determinants of E: I ratio and r-MSSD in healthy subjects. Materials and Methods: 141 healthy subjects were studied. In them body mass index (BMI), Q-T interval, heart rate (HR), systolic, diastolic, pulse and mean arterial blood pressure (MABP) were measured. Age and sex of the subjects were noted. E: I ratio and r-MSSD was estimated from one minute lead II electrocardiogram in supine position. E: I ratio was recorded while breathing at 6 respiratory cycles per minute and r-MSSD was quantified during normal breathing. Data was analyzed by Pearson Correlation Coefficient and unpaired t test. p value less than 0.05 was considered significant. Results: There was positive correlation between E: I ratio and r-MSSD (p = 0.006). E: I ratio and r-MSSD were negatively correlating with age (p < 0.01). r-MSSD was negatively correlating with HR, systolic, diastolic, pulse and MABP (p = 0.0001, 0.01, 0.03, 0.04, 0.01 respectively). r-MSSD did not correlate with BMI and Q-T interval. E: I ratio did not correlate with blood pressure, BMI and Q-T interval. Mean E: I ratio and r-MSSD of males did not differ compared to females. Conclusion: E: I ratio and r-MSSD are correlated. Age is an influencing factor of E: I ratio and r-MSSD. Blood pressure and HR are the other determinants of r-MSSD but not of E: I ratio in healthy subjects. |
| Databáze: | OpenAIRE |
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