Vergleichende histologische und histoautoradiographische untersuchungen an benignen oralen leukoplakien

Autor:	R. Maidhof, H. Rosenberger, F. Prantl, Schell H, Hornstein Op
Rok vydání:	1977
Předmět:	chemistry.chemical_classification Pathology medicine.medical_specialty Dermatology General Medicine Buccal mucosa In vitro Oral leukoplakia stomatognathic diseases Basal cell layer chemistry Keratin medicine Basal membrane Stratum spinosum
Zdroj:	Archives for Dermatological Research. 259:71-82
ISSN:	1432-069X 0340-3696
Popis:	Proliferation was studied in 18 patients with benign oral leukoplakias of the buccal mucosa by in vitro labelling with 3H-TdR. Identical investigations were performed in clinically normal mucosa of the same patients. Significant differences were found between the LI of both groups. On the other hand the total of labelled cells per 100 micron length of the basal membrane was approximately equal in leukoplakias and normal mucosa. In the majority of cases the LI was increased in leukoplakic regions whereas the number of labelled suprabasal cells was lowered compared to normal. These findings are supposed to be a consequence of shifting of epithelial keratinization to the lower stratum spinosum. From that results an increased proliferation in the basal cell layer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::378436e11354b2a2aa2d84070ef96087 https://doi.org/10.1007/bf00562739 Zobrazit plný text záznamu Full text from SpringerLink