Dopaminergic signals for reward, performance and social outcomes are dynamically gated during courtship
| Autor: | Andrea Roeser, Vikram Gadagkar, Anindita Das, Pavel A. Puzerey, Brian Kardon, Jesse H. Goldberg |
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| Rok vydání: | 2019 |
| Předmět: |
0303 health sciences
Communication business.industry media_common.quotation_subject Social environment Context (language use) Courtship 03 medical and health sciences 0302 clinical medicine Dopamine medicine Singing Psychology business 030217 neurology & neurosurgery 030304 developmental biology media_common medicine.drug |
| DOI: | 10.1101/822817 |
| Popis: | How does courtship affect dopaminergic (DA) responses to reward and motor performance outcomes? We used electrophysiology and fiber photometry to record DA signals in two mesostriatal pathways as thirsty male songbirds sang alone and to females. When alone, water reward signals were observed globally but singing-related performance error signals were restricted to a song-specialized mesostriatal pathway. During courtship singing, DA responses to both water-predicting cues and song performance outcomes diminished, and DA signals in the song pathway were instead driven by female calls timed with the male song. Thus DA signals are dynamically gated and routed through distinct pathways as animals change their priorities in response to a courtship opportunity. |
| Databáze: | OpenAIRE |
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