Growth dynamics of incidental meningiomas: A prospective long-term follow-up study

Autor: Torbjørn Austveg Strømsnes, Morten Lund-Johansen, Geir Olve Skeie, Geir Egil Eide, Maziar Behbahani, Bente Sandvei Skeie
Rok vydání: 2022
Předmět:
Zdroj: Neuro-Oncology Practice. 10:238-248
ISSN: 2054-2585
2054-2577
Popis: Background There is no consensus on the management of incidental meningiomas. The literature on long-term growth dynamics is sparse and the natural history of these tumors remains to be illuminated. Methods We prospectively assessed long-term tumor growth dynamics and survival rates during active monitoring of 62 patients (45 female, mean age 63.9 years) harboring 68 tumors. Clinical and radiological data were obtained every 6 months for 2 years, annually until 5 years, then every second year. Results The natural progression of incidental meningiomas during 12 years of monitoring was growth (P Conclusion Active monitoring seems a safe and appropriate first-line management of incidental meningiomas. Intervention was avoided in > 40% with indolent tumors in this cohort. Treatment was not compromised by tumor growth. Clinical follow-up seems sufficient beyond 5 years if self-limiting growth is established. Steady or accelerating growth warrant monitoring until they reach a stable state or intervention is initiated.
Databáze: OpenAIRE