CARDIORESPIRATORY EFFECTS OF DEXMEDETOMIDINE–MIDAZOLAM AND REVERSAL WITH ATIPAMEZOLE IN CAPTIVE BROWN BROCKET DEER (MAZAMA GOUAZOUBIRA)
| Autor: | André Augusto Justo, Silvia Renata Gaido Cortopassi, Mario Antonio Ferraro Rego, Luciano Cacciari Baruffaldi Almeida da Silva, Jose Heitzmann Fontenelle |
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| Rok vydání: | 2021 |
| Předmět: |
0303 health sciences
General Veterinary biology 040301 veterinary sciences business.industry Sedation Atipamezole 04 agricultural and veterinary sciences General Medicine biology.organism_classification 030308 mycology & parasitology Hypoxemia 0403 veterinary science 03 medical and health sciences Blood pressure Anesthesia medicine Midazolam Arterial blood Animal Science and Zoology Dexmedetomidine medicine.symptom Brocket deer business medicine.drug |
| Zdroj: | Journal of Zoo and Wildlife Medicine. 51 |
| ISSN: | 1042-7260 |
| DOI: | 10.1638/2020-0152 |
| Popis: | Ketamine-free, midazolam-based protocols have successfully immobilized cervids in the past but their impact on physiological function has not yet been thoroughly investigated. Six deer received IM dexmedetomidine (30.96 ± 3.06 µg/kg) and midazolam (0.31 ± 0.03 mg/kg). Heart rates (HR), respiratory rates (f ), rectal temperature, mean arterial blood pressure (MAP), and oxygen saturation (SpO2) were recorded 25 min after drug delivery (T25) and every 5 min until T55. An arterial blood sample was collected at T40. Mean HR and temperature significantly decreased throughout sedation, but were maintained above critical values (> 60 beats/ min and 37°C, respectively). Although not statistically different, f clinically decreased during sedation. MAP remained within acceptable ranges (60–80 mmHg) and SpO2 above 95%. Mean PaO2 was normal (>80 mmHg), but a mild hypoxemia was observed on two occasions. Recovery was smooth yet prolonged, as the first head movement, attempt to stand, sternal recumbency, and standing position were recorded within 9.36 ± 3.47, 10.32 ± 1.37, 13.13 ± 2.70, and 15.34 ± 2.57 min after IM atipamezole, respectively. This protocol was effective for short-term procedures in captive brown brocket deer, and appeared to be safe on the basis of arterial blood gases and cardiorespiratory variables. |
| Databáze: | OpenAIRE |
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