| Autor: | Lilia E. Ziganshina, Airat U. Ziganshin, I Kh Valeeva, Burnashova Za |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
biology Pulse therapy General Medicine General Biochemistry Genetics and Molecular Biology Lipid peroxidation chemistry.chemical_compound Hydroxyproline Endocrinology Urinary excretion chemistry Catalase Internal medicine biology.protein medicine Prednisolone Ceruloplasmin Inorganic phosphorus medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 136:62-65 |
| ISSN: | 0007-4888 |
| DOI: | 10.1023/a:1026045031054 |
| Popis: | Experiments on rats showed that pulse therapy with prednisolone (100 mg/kg intraperitoneally for 3 days) stimulated urinary excretion of hydroxyproline, increased the content of inorganic phosphorus, promoted the increase in the content of dienic conjugates and catalase activity, and decreased serum levels of MDA and ceruloplasmin. Ten-day treatment with dimephosphone (208 mg/kg) or xydiphone (45 mg/kg) after pulse therapy with prednisolone normalized urinary excretion of hydroxyproline and reduced the levels of dienic conjugates. Dimephosphone did not change, while xydiphone normalized the level of MDA decreased by prednisolone. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink