Lymphangiosarcoma in 12 dogs: a case series (1998-2013)
| Autor: | K. M. Curran, Deanna R. Worley, C. H. C. Halsey |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Chemotherapy
medicine.medical_specialty General Veterinary 040301 veterinary sciences business.industry medicine.medical_treatment 04 agricultural and veterinary sciences medicine.disease Trunk Carboplatin Surgery 0403 veterinary science 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Prednisone 030220 oncology & carcinogenesis Cytology medicine Lymphangiosarcoma Histopathology Sarcoma business medicine.drug |
| Zdroj: | Veterinary and Comparative Oncology. 14:181-190 |
| ISSN: | 1476-5810 |
| DOI: | 10.1111/vco.12087 |
| Popis: | Lymphangiosarcoma (LAS) is an uncommon malignant neoplasia arising from lymphatic endothelium; little information exists regarding therapy. Single institutional retrospective review for canine LAS histopathology diagnoses over a 15-year period yielded 12 dogs. Ten dogs were presented for a mass and/or swelling at cervical, trunk or limb regions. Prior to diagnosis, 10 dogs received empiric wound therapy. Cytology performed in 10 consisted of mild inflammation. Survival ranged from 60, 168 and 876 days for three dogs with palliation; 90 days with prednisone in one; 182 days with chemotherapy in one; 240, 267, 487, 630 and 941 days for five receiving surgery; and 574 days for one receiving surgery, radiation and chemotherapy. One dog is alive with recurrence at 243 days following surgery and carboplatin chemotherapy. Clinical improvement existed in LAS dogs receiving multimodal therapies. Early tissue biopsies are recommended for progressive oedematous lesions of unknown origin. |
| Databáze: | OpenAIRE |
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