Metal Catalyzed Synthesis of Dihydropyridobenzodiazepines
| Autor: | Chaomin Li, Matthew L. Maddess |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
010405 organic chemistry
Chemistry Organic Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences Catalysis Inorganic Chemistry Metal Coupling (electronics) Cascade visual_art visual_art.visual_art_medium Physical and Theoretical Chemistry Catalytic hydrogenation |
| Zdroj: | Organometallics. 38:81-84 |
| ISSN: | 1520-6041 0276-7333 |
| Popis: | A versatile synthesis of dihydropyridobenzodiazepines that proceeds via a palladium-catalyzed C–N coupling and catalytic hydrogenation cascade is reported. The intermediate 2-anilinonicotinaldehydes may be efficiently protected to ultimately afford N6 differentiated dihydropyridobenzodiazepines, which facilitates further elaboration. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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