ISOLATION, IDENTIFICATION AND QUANTITATIVE DETERMINATION OF NIFEDIPINE FROM BIOLOGICAL MATERIAL

Autor: Satenik Gh. Petrosyan, Lusine Yu. Sahakyan, Virab G. Kirakosyan, Ella V. Minasyan, Siranush Ye. Sardaryan
Rok vydání: 2021
Předmět:
Zdroj: Proceedings of the YSU B: Chemical and Biological Sciences. 55:204-211
ISSN: 1829-1767
DOI: 10.46991/pysu:b/2021.55.3.204
Popis: The optimal conditions of the method, applicable during forensic chemical examinations, were elaborated. Particularly, the investigation of the conditions for the isolation of Nifedipine from liver and skeletal muscle tissues, the identification of the isolated Nifedipine by TLC method and checking the accuracy of the method using HPLC was carried out. As a result, a new alternative express method for the isolation and further identification of Nifedipine from different biomaterials was elaborated. The method is quite fast, accurate and much cheaper.
Databáze: OpenAIRE