Cell Culture and Immune Function Tests

Autor: M. R. Halie, J. T. M. de Wolf, T. Cazemier, W. Huiges, H. E. Modderman, MT Esselink, M.J.A. van Luyn, J. W. Smit, NR Blom
Rok vydání: 1987
Předmět:
Zdroj: White cells and platelets in blood transfusion ISBN: 9781461292388
DOI: 10.1007/978-1-4613-2089-0_23
Popis: Concerning the role of white blood cells in blood transfusions different aspects have to be considered: 1. Antibody formation against HLA and cell specific antigens by the patients immune system. 2. The influence of transfusion on the composition of different white blood cell populations in the patient. Several studies have demonstrated that supportive hemotherapy may influence the immune system: improvement of graft rejection in renal transplantation [1]; alterations in lymphocyte subpopulations in hemophilia patients [2]. 3. The properties and the function of the white blood cells of the donor, which have been collected for transfusion. For instance granulocytes used in transfusion for granulocytopenic patients. But most important are here perhaps the bone marrow grafts now that bone marrow transplantation has become an established procedure in the treatment of hematological disorders.
Databáze: OpenAIRE