Caffeine and SPECT Myocardial Perfusion Imaging
| Autor: | Sarita Konka, Furqan H. Tejani |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Cardiac stress test medicine.disease Adenosine Adenosine receptor Regadenoson Dipyridamole Coronary artery disease chemistry.chemical_compound Myocardial perfusion imaging chemistry Internal medicine medicine Cardiology Caffeine business medicine.drug |
| DOI: | 10.1016/b978-0-12-409517-5.00076-0 |
| Popis: | Coffee is the most widely consumed caffeine product in the United States. Caffeine, being a methylxanthine, exerts antagonist effects on adenosine receptors. Because coronary artery disease is a highly prevalent disease in the United States and intermediate-risk patients are evaluated using cardiac stress testing, the interaction between caffeine and adenosine receptors becomes more important. This is due to the mechanism of vasodilator agents used in these single-photon emission computed tomography (SPECT) myocardial perfusion studies that agonize adenosine receptors. Studies have shown that the antagonist properties of caffeine to these receptors do cause an interference with the results of dipyridamole cardiac stress testing. There are conflicting results regarding limitation on the results of adenosine or regadenoson studies due to coffee intake. The effect of caffeine on exercise stress testing results is limited. Further investigation needs to be performed to assess if coffee abstention is necessary before these types of studies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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