ChemInform Abstract: A Facile and Practical One-Pot Synthesis of Multisubstituted 2-Aminothiophenes via Imidazole-Catalyzed Gewald Reaction

Autor:	Wei-Dong Chen, Xian-Gui Huang, Jiangmeng Ren, Tao Wang, Jia Liu, Bu-Bing Zeng
Rok vydání:	2011
Předmět:	chemistry.chemical_compound Chemistry One-pot synthesis Organic chemistry chemistry.chemical_element Dicyanomethane Imidazole General Medicine Gewald reaction Thiophene derivatives Sulfur Catalysis
Zdroj:	ChemInform. 42
ISSN:	0931-7597
DOI:	10.1002/chin.201151103
Popis:	A simple and efficient procedure was developed for the synthesis of multisubstituted 2-aminothiophene derivatives. In the presence of catalytic amount of imidazole, ketones or aldehydes, dicyanomethane and elemental sulfur were converted into the corresponding 2-aminothiophene derivatives in moderate to high yields in DMF at 60 °C.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::36e0fb217ad29d1afdf1a09049c40737 https://doi.org/10.1002/chin.201151103 Zobrazit plný text záznamu Plný text