Photocyclization of Enamides. XXVIII. : A Formal Total Synthesis of (±)-Deserpidine

Autor:	Katsuhisa Kamiichi, Ichiya Ninomiya, Masatoshi Inoue, Yumiko Hirata, Takeaki Naito, Mitsunobu Doi, Okiko Miyata
Rok vydání:	1989
Předmět:	Indole alkaloid Chemistry medicine.medical_treatment Alkaloid Total synthesis Regioselectivity Deserpidine General Chemistry General Medicine Reserpine chemistry.chemical_compound Drug Discovery medicine Organic chemistry Enone medicine.drug
Zdroj:	Chemical and Pharmaceutical Bulletin. 37:901-906
ISSN:	1347-5223 0009-2363
DOI:	10.1248/cpb.37.901
Popis:	A formal total synthesis of (±)-deserpidine (1) was accomplished by preparing the known synthetic precursors, two hydroxyesters 19 and 20, via a route involving regioselective formation of the 18-methoxyenone 10a followed by regioselective C-acylation of the enone 10a.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::36d7e99d482c70ac87ff4eae7a9f1aaf https://doi.org/10.1248/cpb.37.901 Zobrazit plný text záznamu