THE EFFECT OF METHIPHENE, METHIONINE, AND PHENARONE ON THE HUMORAL PART OF THE IMMUNE SYSTEM OF PIGLETS IN EXPERIMENTAL CHRONIC NITRATE-NITRITE TOXICOSIS

Autor: Leskiv Kh Ya., Gufriy D.F., Gutyj B.V., Khalak V. I., Hariv I.I., Martyshuk T.V., Guta, Z.A.
Rok vydání: 2021
Předmět:
DOI: 10.24412/2520-6990-2021-794-12-15
Popis: The article describes the dynamics of indicators of the state of humoral immunity of piglets in experimental nitrate-nitrite toxicosis. The subjects were 20 large white piglets three months old. The research was conducted at the Komarnivsky National Research Center of the Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies. According to the method of analog groups, one control and three experimental were formed. Feeding sodium nitrate to piglets at a dose of 0.3 g NO3ˉ/kg. b.w. contributes to the development of chronic nitrite-nitrate toxicosis. Nitrates in a toxic dose for 90 days reduce the protective properties of the body. Under nitrate load, feeding pigs phenarone, methyphene, and methionine had a positive effect on piglets' humoral immunity, manifested by the high antimicrobial activity of serum.
Databáze: OpenAIRE