RELATIONSHIP BETWEEN METRONIDAZOLE AND CO-TRIMOXAZOLE ON ERADICATION OF ENTAMOEBA HISTOLYTICA
| Autor: | Ftimeh Naemat, Sameer Mahmoud Alshiab, Mohammed Issa Aladwan, Eman F. Khreisat, Nadia Al Smadi, Amal F. Khreisat, Ghadah Al Abdallat, Ahamad Al-Ali Fbms, Fatima Mohammad Aburumman, Yazun Jarrar, Mohammed Ali Abu-Rumman |
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| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
biology business.industry Entamoeba Stool examination Emergency department biology.organism_classification medicine.disease Pediatric clinic Surgery Metronidazole Entamoeba histolytica Diarrhea Internal medicine medicine General Earth and Planetary Sciences Cyst medicine.symptom business General Environmental Science medicine.drug |
| Zdroj: | American Journal of Microbiology. 3:31-33 |
| ISSN: | 1948-982X |
| Popis: | To present the efficacy and safety of Metronidazole and co-trimoxazole in the treatment of diarrhea ca used by Entamoeba histolytica, cyst and trophozyed in pa tients presented to the emergency department and emergency pediatric clinic in Queen Alia Hospital ( Jordan). A strategy for diagnosis Entamoeba histoly tica was evaluated by studying 181 patients aged 2-50 ye ars. Between the 1st of May 2009 and the beginning of May 2010, 181 patients with intestinal amoebiasis w ere recruited for this study from the Emergency Department and emergency Pediatric Clinic at Queen Alia Military Hospital. After doing stool analysis for every patient, Metronidazole 500 mg three times was given to the adult group and 40 mg kg -1 day in three divided doses for the pediatric group for 10 days a nd two tablets twice daily for adults and 5 mL twic e daily for children for ten days of co-trimaxazole, with f ollow up stool analysis after one week of treatment . Out of 181 patients (81) patients were adult’s age (14-50 years) and (100 patients) were children aged (2-14 years). About 5.5% of the patient showed the amoebic trophozoite in their stool while the remaining showed onl y the amoebic cysts. Over all metronidazole and co-tr imoxazole produced a clinical response rate of 95% in both adults and children group after 10 days course of Metronidazole. Our findings demonstrated the efficacy of 10 day of course Metronidazole and co-t rimoxazole in eradication intestinal amoebiasis for which the causative organism is identified by simpl e stool examination. |
| Databáze: | OpenAIRE |
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