An Efficient, One-Pot Synthesis of 1,3-Disubstituted imidazo[1,5-a]pyridines, Fe(OTf)3 Mediated C-C Bond Formation

Autor: T.C. Raveesha, null Kemparajegowda, Hassan A. Swarup, B.K. Kempegowda, T. Demappa
Rok vydání: 2023
Předmět:
Zdroj: Asian Journal of Chemistry. 35:1225-1230
ISSN: 0975-427X
0970-7077
Popis: A vital approach of Fe(OTf)3 and MS3Å (molecular sieves 3Å) mediated one pot synthesis of 1,3-disubstituted imidazo[1,5-a]pyridines from dithioester, 2-methylaminopyridine and alcohol. This methodology involves the intramolecular cyclization and C–C bond formation under mild condition and operates in a single step yielding the products in good to excellent yields. This protocol was compatible to construct various 1,3-disubstituted imidazo[1,5-a] pyridines derivatives.
Databáze: OpenAIRE