Incorporation of vancomycin-supplemented bone allograftsRadiographical, histopathological and immunohistochemical study in pigs
| Autor: | Francisco Piccaluga, Esteban Mocetti, Ana Morandi, Alejandro Gonzalez Della Valle, Laura Pineiro, Martin Buttaro |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Pathology
medicine.medical_specialty Chemotherapy medicine.drug_class business.industry medicine.medical_treatment Antibiotics chemical and pharmacologic phenomena Anatomical pathology Minimum inhibitory concentration surgical procedures operative In vivo medicine Vancomycin Orthopedics and Sports Medicine Surgery Histopathology business Antibacterial agent medicine.drug |
| Zdroj: | Acta Orthopaedica Scandinavica. 74:505-513 |
| ISSN: | 0001-6470 |
| DOI: | 10.1080/00016470310017884 |
| Popis: | We compared the incorporation of bone allografts with or without vancomycin in tibial defects of 18 pigs. High-quality radiographs, histological examination, immunological expression of metalloproteinase-13 (MMP-13) and transforming growth factor-beta 2 (TGFs2) indicated that there was no significant difference in bone allograft incorporation between up to 220 times the MIC (minimum inhibitory concentration) in bone allografts with 1 g of vancomycin in each 300 g of allograft or without this supplement. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|