Color vision deficiency in retinitis pigmentosa

Autor: Peter Herse, Stephan Dain, Rokiah Omar
Rok vydání: 2005
Předmět:
Zdroj: International Congress Series. 1282:684-688
ISSN: 0531-5131
DOI: 10.1016/j.ics.2005.05.170
Popis: Purpose This study examined which color vision test was superior in the detection of acquired color vision deficiencies and the relative magnitudes of red–green (RG) and blue–yellow (BY) discrimination losses in retinitis pigmentosa (RP). Methods Color vision examinations were conducted using Standard Pseudoisochromatic Plates Part 2 (SPP Part 2) and a flicker threshold test (TMT) in 21 RP and 21 age- and sex-matched normals. The TMT test consists of luminance, BY and RG flicker tests. Relative Operating Characteristic analysis (ROC) was used to determine the effectiveness of each test. Bigger ROC area gain and high performance (%) indicate a better test. Regression and correlation analyses were used to determine the relative magnitudes of RG and BY discrimination losses for the SPP Part 2. For TMT the findings were represented graphically where the mean log sensitivity was plotted against the frequency of mean luminance; RG and BY flicker individually and the range was plotted with the 5th and 95th percentile. Results Both tests were able to determine BY and RG acquired color vision deficiencies in RP patients. SPP Part 2 showed the highest area gain (0.39) and performance (78%). The TMT generally showed less area gain and performance compared to SPP Part 2. Pearson's correlation coefficient analysis on the RG and BY SPP Part 2 test plates showed a strong relationship (r = 0.96, p Conclusions The SPP Part 2 appears to be a superior test compared to TMT in detecting acquired color vision deficiencies in RP patients. RP subjects also suffer both RG and BY acquired color vision deficiencies.
Databáze: OpenAIRE