Periodontal disease and type 2 diabetes: effects on salivary enzyme activities
| Autor: | Emeka E Neboh, Ebele J. Ikekpeazu, Ignatius C. Maduka, Nochie S. Okenyi, Emeka G. Anyanwu |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Saliva biology business.industry Endocrinology Diabetes and Metabolism Acid phosphatase Aspartate transaminase Type 2 diabetes medicine.disease Gastroenterology chemistry.chemical_compound Endocrinology chemistry Internal medicine Diabetes mellitus Lactate dehydrogenase Internal Medicine medicine biology.protein Alkaline phosphatase Creatine kinase business |
| Zdroj: | International Journal of Diabetes in Developing Countries. 31:9-13 |
| ISSN: | 1998-3832 0973-3930 |
| DOI: | 10.1007/s13410-010-0005-z |
| Popis: | There has been correlation between type 2 diabetes and periodontal disease and numerous markers in saliva, such as intracellular enzymes, which have been proposed as diagnostic tests for periodontal diseases. The present study estimates the activities of some salivary enzymes as possible means of diagnosis and treatment monitoring of periodontal disease patients with type 2 diabetes. A total of 320 subjects, of both sexes, aged 28–81 years were included in the study and divided into four groups of 80 subjects each. The groups were non-diabetics with periodontal disease, type 2 diabetics with periodontal disease, type 2 diabetics without periodontal disease and apparently healthy non-diabetics (controls). The activities of the enzymes, acid phosphatase (ACP), alkaline phosphatase (ALP), alanine transmainase (ALT), aspartate transaminase (AST), creatine kinase (CK) and lactate dehydrogenase (LDH) were determined in saliva of the subjects using standard spectrophotometric methods. For data analysis, paired students t-test was done using SPSS computer software and the results are presented as mean±SD. The enzyme activities (U/L) investigated showed significant differences (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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